Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726290 | 0.88 | LMNA (0.56) | NR1H4LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6239639 | 0.83 | NR1H4 (0.73) | GAANR1H4POLBCHRNB2CHRNB4 | |
| SCHEMBL3307141 | 0.82 | MAPT (0.57) | GAAPOLBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL3726623 | 0.82 | MAPT (0.45) | GAANR1H4POLBCHRNB2CHRNB4 | |
| SCHEMBL3729018 | 0.81 | NR1H4 (0.48) | GAANR1H4POLBCHRNB2CHRNB4 | |
| SCHEMBL3973235 | 0.81 | ALDH1A1 (0.65) | NR1H4LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL13566609 | 0.80 | SGMS2 (0.69) | GAALMNAMAPTSMN1; SMN2FFAR1 | |
| SCHEMBL6795782 | 0.80 | FFAR1 (0.67) | GAANR1H4POLBCHRNB2CHRNB4 | |
| SCHEMBL3726975 | 0.80 | POLB (0.56) | GAANR1H4POLBLMNAMAPT | |
| SCHEMBL3731267 | 0.80 | MTTP (0.46) | NR1H4LMNAMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |