Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465591 | 0.92 | ERN1 (0.42) | MAPTCRHBPCRHR2ERN1LMNA | |
| SCHEMBL6459325 | 0.91 | ALDH1A1 (0.42) | MAPTERN1LMNAPOLBALDH1A1 | |
| SCHEMBL7643417 | 0.90 | ERN1 (0.38) | MAPTERN1LMNAPOLBALDH1A1 | |
| SCHEMBL6465588 | 0.89 | ERN1 (0.43) | MAPTERN1LMNACYP2D6POLB | |
| SCHEMBL6233340 | 0.89 | ERN1 (0.43) | MAPTERN1LMNACYP2D6POLB | |
| SCHEMBL14634986 | 0.82 | PTGDR2 (0.46) | MAPTERN1LMNACYP2C19NPSR1 | |
| SCHEMBL11755152 | 0.79 | TDP1 (0.42) | MAPTLMNACYP3A4NPSR1POLB | |
| SCHEMBL2562538 | 0.78 | ERN1 (0.46) | MAPTERN1CYP2D6POLBALDH1A1 | |
| SCHEMBL28825735 | 0.76 | MAPT (0.55) | MAPTERN1LMNACYP3A4CYP2D6 | |
| SCHEMBL31327257 | 0.76 | MAPT (0.55) | MAPTERN1LMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222159-B1 | INTERMEDIATES FOR MAKING A BENZOFURAN OR BENZOTHIOPHENE DERIVATIVE NITRATED IN POSITION 5 AND USES THEREOF | RHODIA CHIMIE SA (FR) | 2005-06-01 | — | — | EP | claimed |