Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459325 | 0.92 | ALDH1A1 (0.42) | ERN1POLBALDH1A1TDP1CYSLTR2 | |
| SCHEMBL6237455 | 0.92 | MAPT (0.42) | ERN1POLBALDH1A1TDP1CYSLTR2 | |
| SCHEMBL6233340 | 0.90 | ERN1 (0.43) | ERN1POLBALDH1A1TDP1CYSLTR2 | |
| SCHEMBL6465588 | 0.90 | ERN1 (0.43) | ERN1POLBALDH1A1TDP1CYSLTR2 | |
| SCHEMBL7643417 | 0.89 | ERN1 (0.38) | ERN1POLBALDH1A1TDP1CYSLTR2 | |
| SCHEMBL2562538 | 0.79 | ERN1 (0.46) | ERN1POLBALDH1A1TDP1MAPT | |
| SCHEMBL31327257 | 0.77 | MAPT (0.55) | ERN1ALDH1A1TDP1CYSLTR2CYSLTR1 | |
| SCHEMBL28825735 | 0.77 | MAPT (0.55) | ERN1ALDH1A1TDP1CYSLTR2CYSLTR1 | |
| SCHEMBL15331896 | 0.75 | ERN1 (0.49) | ERN1POLBALDH1A1TDP1LMNA | |
| SCHEMBL9480938 | 0.74 | CYP19A1 (0.57) | ERN1ALDH1A1CYSLTR2CYSLTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855842-B1 | Intermediates for making a bezofuran or benzothiophene derivative nitrated in position 5 and uses thereof | RHODIA CHIMIE (FR) | 2005-02-15 | — | — | US | disclosed |