SCHEMBL6237462

SCHEMBL6237462

NC(=S)Cc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.50
LMNA P02545 1/20 0.49
RAB9A P51151 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
LIN28A Q9H9Z2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PLAU P00749 1/20 0.44
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
PARP10 Q53GL7 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30940202 1.00 HRH1 (0.50) HRH1LMNARAB9ACA12CA1
Hydrochloric Acid SCHEMBL6990559 0.98 LMNA (0.51) HRH1LMNARAB9ACA12CA1
SCHEMBL7890898 0.83 HRH1 (0.54) HRH1LMNARAB9ANPC1SMN1; SMN2
SCHEMBL7890891 0.83 HRH1 (0.54) HRH1LMNARAB9ANPC1SMN1; SMN2
SCHEMBL6400020 0.81 RAB9A (0.47) HRH1RAB9ACA12CA1CA2
Pyridine Acetamide SCHEMBL29431271 0.79 RAB9A (0.54) HRH1LMNARAB9ACA1CA2
SCHEMBL2780427 0.79 SMN1; SMN2 (0.48) HRH1RAB9ACA12CA1CA2
Pyridine Acetamide SCHEMBL176893 0.79 RAB9A (0.54) HRH1LMNARAB9ACA1CA2
SCHEMBL5850990 0.79 HRH1 (0.50) HRH1LMNARAB9ACA1CA2
SCHEMBL7358602 0.79 CA12 (0.50) HRH1LMNARAB9ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137555-A1 POLYPEPTIDES THAT BIND TO NKP46 OMNIAB, INC. (US) 2025-06-26 WO disclosed
US-20250018489-A1 Brazing Method, Brazed Joint, and Braze ABB SCHWEIZ AG (CH) 2025-01-16 US disclosed
CN-119192939-A High-hardness scratch-resistant artistic coating and preparation method and application thereof 广东卡百利新材料科技有限公司 2024-12-27 CN disclosed
CN-115446407-B Brazing method of high-volume-fraction SiCp/Al-based composite material and AlN ceramic 中国航发北京航空材料研究院 2024-10-29 CN disclosed
CN-118872015-A Soldering method, soldered joint and solder ABB瑞士股份有限公司 2024-10-29 CN disclosed
CN-118165161-B Resin containing pyridine-thioacetamide structure, and preparation method and application thereof 上海稀固科技有限公司 2024-07-02 CN disclosed
CN-118165161-A Resin containing pyridine-thioacetamide structure, and preparation method and application thereof 上海稀固科技有限公司 2024-06-11 CN disclosed
CN-113166848-B Conductive material excellent in abrasion resistance and heat resistance 田中贵金属工业株式会社 2024-02-06 CN disclosed
WO-2023186753-A1 BRAZING METHOD, BRAZED JOINT, AND BRAZE ABB SCHWEIZ AG (CH) 2023-10-05 WO disclosed
EP-4254452-A1 BRAZING METHOD, BRAZED JOINT, AND BRAZE ABB SCHWEIZ AG (CH) 2023-10-04 EP disclosed
CN-115446407-A Brazing method of high-volume-fraction SiCp/Al-based composite material and AlN ceramic 中国航发北京航空材料研究院 2022-12-09 CN disclosed
CN-115417686-A Connecting AlON/Al 2 O 3 Method for producing ceramic 大连海事大学 2022-12-02 CN disclosed
US-20190039046-A1 ADSORBENT MATERIAL AND PURIFICATION METHOD HITACHI, LTD. (JP) 2019-02-07 US disclosed
WO-2005009435-A1 AMINOPYRAZOLE COMPOUNDS AND USE AS CHK1 INHIBITORS PFIZER INC. (US) 2005-02-03 WO disclosed
US-4118567-A 3-Morpholino-2-heterocyclic-thiopropanamides SMITHKLINE CORPORATION (US) 1978-10-03 US disclosed
US-3950522-A N-ALKENYL OR N-ALKYNYL THIOAMIDES SMITHKLINE CORPORATION (US) 1976-04-13 US disclosed
US-3933811-A N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides SMITHKLINE CORPORATION (US) 1976-01-20 US disclosed
US-3932641-A THIOACETAMIDES SMITHKLINE CORPORATION (US) 1976-01-13 US disclosed
US-3931162-A N-Aminomethyl heterocyclic thioacetamides SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed
US-3898228-A N-alkenyl and N-alkynyl 2-pyridine thioacetamides SMITHKLINE BECKMAN CORPORATION 1975-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190039046-A1 ADSORBENT MATERIAL AND PURIFICATION METHOD TACR2, ADGRF1, ACP1 HRH1 1126/4885LMNA 2695/4885RAB9A 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.