Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400020 | 0.81 | RAB9A (0.47) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL30940202 | 0.79 | HRH1 (0.50) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL6237462 | 0.79 | HRH1 (0.50) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL1258953 | 0.79 | RAB9A (0.54) | CA1CA2RAB9ANPC1HRH1 | |
| SCHEMBL2780427 | 0.79 | SMN1; SMN2 (0.48) | CA12CA1CA2CA9RAB9A | |
| Hydrochloric Acid SCHEMBL6990559 | 0.78 | LMNA (0.51) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL21909733 | 0.75 | RAB9A (0.54) | CA1CA2RAB9ANPC1HRH1 | |
| SCHEMBL5432067 | 0.75 | RAB9A (0.54) | CA1CA2RAB9ANPC1HRH1 | |
| SCHEMBL29612049 | 0.75 | HRH3 (0.50) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL11638957 | 0.75 | HRH3 (0.50) | CA12CA1CA2CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |