Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16699914 | 0.78 | CHRNB2 (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7622671 | 0.75 | CHRM1 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12734604 | 0.71 | CTSK (0.42) | CA1CA2 | |
| SCHEMBL12734615 | 0.71 | CTSK (0.42) | CA1CA2 | |
| SCHEMBL28100539 | 0.71 | CTSK (0.42) | CA1CA2 | |
| SCHEMBL25097363 | 0.71 | CHRM1 (0.33) | CHRM1CHRM3CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL16000128 | 0.71 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22305475 | 0.70 | ACE2 (0.42) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7047130 | 0.69 | MAPT (0.37) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7047126 | 0.69 | MAPT (0.37) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532114-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | claimed |
| WO-2004013103-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-12 | — | — | WO | claimed |