Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237602 | 0.75 | CHRM2 (0.44) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL8434420 | 0.73 | CHRM2 (0.48) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL8633705 | 0.73 | CHRM1 (0.39) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL6524092 | 0.71 | CHRM2 (0.43) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL16000128 | 0.70 | CHRM2 (0.50) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL23339733 | 0.69 | FAAH (0.32) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL8299206 | 0.69 | CHRM1 (0.32) | CHRM1CHRM3AKR1A1HTR2AHTR2C | |
| SCHEMBL321052 | 0.69 | — | — | |
| SCHEMBL15860390 | 0.69 | CHRM1 (0.50) | CHRM1CHRM3AKR1A1HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL8588154 | 0.68 | CHRM2 (0.44) | CHRM1CHRM3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137672-A1 | Radiolabeled annexins | KASINA SUDHAKAR (US) | 2002-09-26 | — | — | US | disclosed |
| US-6171577-B1 | ACCESSIBLE SULFHYDRYL GROUP; AND HEXOSE MOIETY RECOGNIZED BY A MAMMALIAN LIVER RECEPTOR, WHEREIN THE HEXOSE MOIETY IS CONJUGATED TO THE ANNEXIN. | NEORX CORPORATION | 2001-01-09 | — | — | US | disclosed |
| US-5985826-A | Methods of using hepatic-directed compounds in pretargeting strategies | NEORX CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| US-5968477-A | IMAGING AGENTS WITH SULFHYDRYL GROUPS AND HEXOSE GROUPS | NEORX CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0918547-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997046098-A9 | CLUSTER CLEARING AGENTS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1998004294-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137672-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | CHRM1 4434/4885CHRM3 4051/4885CHRM2 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.