SCHEMBL6237802

SCHEMBL6237802

Nc1nc(N)nc(N)n1.O=c1[nH]c(=O)[nH]c(=O)[nH]1.O=c1[nH]c(=O)[nH]c(=O)[nH]1.O=c1[nH]c(=O)[nH]c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 1/20 0.41
RPS6KA3 P51812 1/20 0.38
TYMP P19971 4/20 0.36
PNP P00491 2/20 0.36
CASP1 P29466 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
BLM P54132 1/20 0.35
MITF O75030 1/20 0.34
TP53 P04637 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CTSK P43235 2/20 0.32
CDK1 P06493 1/20 0.31
CDK4 P11802 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159174 1.00 L3MBTL1 (0.41) L3MBTL1MAPTRPS6KA3TYMPPNP
SCHEMBL21828456 1.00 L3MBTL1 (0.41) L3MBTL1MAPTRPS6KA3TYMPPNP
SCHEMBL28223585 0.81 HSP90AA1 (0.38) L3MBTL1MAPTRPS6KA3PNPCYP3A4
SCHEMBL10724916 0.81 HRH4 (0.41) L3MBTL1MAPTTYMPCASP1CYP1A2
SCHEMBL383327 0.81 DPYD (0.32) L3MBTL1MAPT
SCHEMBL10730184 0.79 CASP1 (0.48) L3MBTL1MAPTCASP1CYP1A2
SCHEMBL5321890 0.79 L3MBTL1 (0.42) L3MBTL1MAPTRPS6KA3PNPCYP3A4
Carbon Dioxide SCHEMBL28176337 0.74 CASP1 (0.40) CASP1CYP1A2LMNA
Hydrazine SCHEMBL27800713 0.73 IDH1 (0.39) MAPTTYMPPNPALDH1A1PDE3B
SCHEMBL9062085 0.73 IDH1 (0.44) MAPTTYMPPNPCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1544271-A1 Blocked isocyanates for clearcoats BASF CORPORATION (US) 2005-06-22 EP disclosed
US-20050129865-A1 Blocked isocyanates for clearcoats without usage restrictions BASF CORPORATION 2005-06-16 US disclosed
US-5686539-A Thermoplastic compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-11 US disclosed
EP-0440923-B1 Polyolefin resin compositions and process for producing same SUMITOMO CHEMICAL CO (JP) 1997-06-04 EP disclosed
US-5635570-A THERMOPLASTIC MOLDING MATERIALS; HOMOGENEITY, IMPACT STRENGTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-03 US disclosed
US-5587427-A MELTING, KNEADING A POLYOLEFIN, A FUNCTIONAL COMPOUND AND APOLAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-12-24 US disclosed
US-5561199-A CONTAINING POLYPHENYLENE ETHER, POLYARYLENE SULFIDE, POLYISOCYANATE; IMPACT STRENGTH SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1996-10-01 US disclosed
EP-0440922-B1 Resin compositions SUMITOMO CHEMICAL CO (JP) 1996-03-20 EP disclosed
US-5475054-A Improving the compatibility of polyether and addition polymer by modifying each polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-12-12 US disclosed
US-5449721-A Thermoplastic resin compositions comprising polyphenylene ether, polyamide and fluorocarbon resins SUMITOMO CHEMICAL CO., LTD. (JP) 1995-09-12 US disclosed
EP-0658602-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-21 EP disclosed
EP-0636658-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-01 EP disclosed
US-5336713-A Polyphenylene ether and a polyarylene sulfide; excellent welding property SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-09 US disclosed
EP-0570972-A1 Polyphenylene ether polyarylene sulfide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-24 EP disclosed
EP-0568039-A1 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 EP disclosed
US-5218048-A Blend of thermoplastic resin, functional monomer and diamino compound; impact strength, stiffness SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-08 US disclosed
EP-0542296-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-19 EP disclosed
US-5189103-A Blend with polyolefin; impact strength, solvent resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-23 US disclosed
EP-0440923-A1 Polyolefin resinsompositions and process for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed
EP-0440922-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed