Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911087 | 0.77 | MEN1 (0.52) | CYP1A2CYP2C19ALOX15HSD17B10MAPT | |
| SCHEMBL1699587 | 0.77 | MEN1 (0.52) | CYP1A2CYP2C19ALOX15HSD17B10MAPT | |
| SCHEMBL5368754 | 0.77 | ALOX15 (0.56) | CYP1A2CYP2C19RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11867307 | 0.76 | PPARG (0.43) | RAB9ASMN1; SMN2NPC1HSD17B10MAPT | |
| SCHEMBL6241934 | 0.76 | POLB (0.56) | RAB9AALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL11869605 | 0.73 | PPARG (0.43) | RAB9ASMN1; SMN2NPC1HSD17B10MAPT | |
| SCHEMBL104746 | 0.70 | CA2 (0.62) | RAB9AHSD17B10MAPTLMNAKDM4E | |
| SCHEMBL10717547 | 0.70 | AKR1B1 (0.63) | CYP2C19RAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL11859884 | 0.69 | CA2 (0.67) | RAB9ASMN1; SMN2HSD17B10MAPTLMNA | |
| SCHEMBL21142097 | 0.69 | SMN1; SMN2 (0.47) | CYP1A2CYP2C19RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |