Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911087 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL837008 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL151879 | 0.85 | TSHR (0.50) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL31306705 | 0.85 | TSHR (0.50) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24173290 | 0.83 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL29718887 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1395757 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL30941510 | 0.83 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2395772 | 0.82 | TSHR (0.54) | MEN1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL29673144 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114715-B1 | P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS | SIEMENS AG (DE) | 2019-10-30 | — | — | EP | claimed |
| EP-3114715-A1 | P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS | Siemens Aktiengesellschaft (DE) | 2017-01-11 | — | — | EP | claimed |
| EP-0710648-B1 | Method for producing oxyindoles | KI CHEMICAL INDUSTRY CO LTD (JP) | 2002-04-03 | — | — | EP | claimed |
| US-5679799-A | Method for producing oxyindoles | K-I CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0710648-A1 | Method for producing oxyindoles | K I CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-08 | — | — | EP | claimed |
| US-12599587-B2 | Chlorinated tetralin compounds and pharmaceutical compositions | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260034099-A1 | CHLORINATED TETRALIN COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | SPRINGWORKS THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4079724-B1 | 2-(2-CHLOROPHENYL)-N-(5-SULFAMOYLISOQUINOLIN-7-YL)ACETAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS P2X4 ANTAGONISTS FOR THE TREATMENT OF E.G. URINARY TRACT DISEASES | WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) | 2025-11-12 | — | — | EP | disclosed |
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | BNH RESEARCH CO., LTD. (KR) | 2025-06-12 | — | — | US | disclosed |
| US-20250185502-A1 | ORGANIC OPTOELECTRONIC COMPONENT, ORGANIC FUNCTIONAL LAYER, AND METHOD FOR PRODUCING AN OPTOELECTRONIC COMPONENT | OSRAM OLED GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| US-12302747-B2 | Optoelectronic component, organic functional layer, and method for producing an optoelectronic component | OSRAM OLED GMBH (DE) | 2025-05-13 | — | — | US | disclosed |
| WO-2025071368-A1 | POLYMORPHS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND USES THEREOF | 주식회사 비엔에이치리서치 | 2025-04-03 | — | — | WO | disclosed |
| WO-2000059497-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0977989-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5925527-A | SCREENING NEW PHARMACEUTICALS | TREGA BIOSCIENCES, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| US-5679799-A | Method for producing oxyindoles | K-I CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0710648-A1 | Method for producing oxyindoles | K I CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034099-A1 | CHLORINATED TETRALIN COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | BACE1, BACE2, DSG1 | MEN1 295/4885KMT2A 329/4885ALDH1A1 3125/4885 |
| US-12599587-B2 | Chlorinated tetralin compounds and pharmaceutical compositions | CLIC1, CLCN2, CSNK1D | MEN1 616/4885KMT2A 952/4885ALDH1A1 1962/4885 |
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | NLN, GRIN1, GRIN2A | MEN1 3053/4885KMT2A 687/4885ALDH1A1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.