Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 7/20 | 0.53 |
| ▸ | CHRND | Q07001 | 5/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.53 |
| ▸ | CHRNG | P07510 | 1/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936553 | 0.93 | TLR2 (0.58) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL6936560 | 0.93 | TLR2 (0.58) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL6243112 | 0.86 | POLB (0.48) | — | |
| SCHEMBL506862 | 0.85 | TLR2 (0.53) | TLR2 | |
| SCHEMBL506861 | 0.85 | TLR2 (0.53) | TLR2 | |
| SCHEMBL7217135 | 0.83 | ITGA4 (0.46) | — | |
| SCHEMBL6241121 | 0.83 | TLR2 (0.51) | TLR2 | |
| SCHEMBL6934205 | 0.80 | NAAA (0.56) | TLR2 | |
| SCHEMBL6241805 | 0.80 | NAAA (0.56) | TLR2 | |
| SCHEMBL6930474 | 0.80 | NAAA (0.56) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |