Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623329 | 0.93 | CTSB (0.54) | CTSBSMN1; SMN2CTSD | |
| SCHEMBL622823 | 0.93 | CTSB (0.54) | CTSBSMN1; SMN2CTSD | |
| SCHEMBL622810 | 0.92 | CTSB (0.53) | CTSBSMN1; SMN2CTSD | |
| SCHEMBL623362 | 0.87 | CTSB (0.58) | CTSBSMN1; SMN2CTSDCAPN1 | |
| SCHEMBL23234647 | 0.86 | CTSB (0.58) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL622149 | 0.85 | CTSB (0.51) | CTSBCAPN1 | |
| SCHEMBL623001 | 0.85 | CTSB (0.50) | CTSBCAPN1 | |
| SCHEMBL622495 | 0.84 | CTSB (0.58) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL10084312 | 0.84 | CTSB (0.53) | CTSBSMN1; SMN2CTSD | |
| SCHEMBL10084537 | 0.84 | CTSB (0.51) | CTSBSMN1; SMN2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |