Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSH | P09668 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622810 | 0.99 | CTSB (0.53) | CTSBCTSDSMN1; SMN2CTSKCTSL | |
| SCHEMBL623329 | 0.98 | CTSB (0.54) | CTSBCTSDSMN1; SMN2CTSKCTSL | |
| SCHEMBL623797 | 0.93 | CTSB (0.56) | CTSBCTSDSMN1; SMN2 | |
| SCHEMBL622149 | 0.92 | CTSB (0.51) | CTSB | |
| SCHEMBL623001 | 0.91 | CTSB (0.50) | CTSB | |
| SCHEMBL622356 | 0.90 | CTSB (0.45) | CTSBCTSD | |
| SCHEMBL10084885 | 0.89 | CASP1 (0.46) | CTSBCTSDCTSK | |
| SCHEMBL621504 | 0.89 | CTSB (0.44) | CTSB | |
| SCHEMBL622452 | 0.89 | CASP1 (0.45) | CTSBCTSDCTSK | |
| SCHEMBL622775 | 0.88 | CTSB (0.52) | CTSBCTSDCTSKCTSLCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |