Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | IL1B | P01584 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621818 | 0.94 | CTSB (0.53) | CTSBCTSDCASP1ACEIL1B | |
| SCHEMBL622416 | 0.94 | CTSB (0.54) | CTSBCTSDCASP1ACEIL1B | |
| SCHEMBL623363 | 0.93 | CTSB (0.53) | CTSBCTSDCASP1IL1BSMN1; SMN2 | |
| SCHEMBL10084539 | 0.93 | CTSB (0.53) | CTSBCTSDCASP1 | |
| SCHEMBL623793 | 0.92 | ALDH1A1 (0.54) | CTSBCTSDCASP1 | |
| SCHEMBL10084534 | 0.92 | CTSB (0.51) | CTSBCTSDCASP1IL1BSMN1; SMN2 | |
| SCHEMBL623259 | 0.91 | CTSB (0.53) | CTSBCTSDCASP1 | |
| SCHEMBL621711 | 0.90 | CTSB (0.54) | CTSBACECAPN1 | |
| SCHEMBL10084324 | 0.89 | CTSB (0.48) | CTSBCTSDCASP1SMN1; SMN2CAPN1 | |
| SCHEMBL622850 | 0.89 | CTSB (0.48) | CTSBCTSDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072212-A1 | PROTEASOME INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |