Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15939773 | 1.00 | LMNA (0.47) | LMNATSHRL3MBTL1MAPTTDP1 | |
| SCHEMBL12248173 | 0.82 | LMNA (0.45) | LMNATSHRL3MBTL1KDM4EPOLB | |
| SCHEMBL30172716 | 0.80 | LMNA (0.61) | LMNATSHRL3MBTL1KDM4ERECQL | |
| SCHEMBL5107133 | 0.80 | LMNA (0.61) | LMNATSHRL3MBTL1KDM4ERECQL | |
| SCHEMBL5107136 | 0.80 | LMNA (0.61) | LMNATSHRL3MBTL1KDM4ERECQL | |
| SCHEMBL5107130 | 0.80 | LMNA (0.61) | LMNATSHRL3MBTL1KDM4ERECQL | |
| SCHEMBL16771466 | 0.79 | L3MBTL1 (0.43) | TSHRL3MBTL1MAPTTDP1EGFR | |
| SCHEMBL28685725 | 0.78 | TSHR (0.58) | LMNATSHRL3MBTL1MAPK1RAB9A | |
| SCHEMBL8811036 | 0.78 | TSHR (0.58) | LMNATSHRL3MBTL1MAPK1RAB9A | |
| SCHEMBL23341753 | 0.78 | TSHR (0.55) | LMNATSHRL3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527034-A1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE | FIRMENICH SA (CH) | 2005-05-04 | — | — | EP | claimed |
| WO-2004013069-A1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A PRECURSOR OF SCLAREOLIDE | FIRMENICH SA (CH) | 2004-02-12 | — | — | WO | claimed |
| US-5149821-A | Process and intermediates for optically active 3-formyltetrahydropyrans | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-4277420-A | Ephedrine and pseudoephedrine precursors | MONSANTO COMPANY (US) | 1981-07-07 | — | — | US | disclosed |