Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 1.00 |
| ▸ | RXRB | P28702 | 9/20 | 1.00 |
| ▸ | RXRG | P48443 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22480752 | 0.85 | MRGPRX4 (0.76) | RXRARXRBRXRGHPGDMRGPRX4 | |
| SCHEMBL9446223 | 0.84 | RXRA (0.71) | RXRARXRBRXRGMRGPRX4KDM4E | |
| SCHEMBL5030365 | 0.84 | RXRA (0.72) | RXRARXRBRXRGNR4A2PTGER1 | |
| SCHEMBL8460349 | 0.84 | RXRA (0.72) | RXRARXRBRXRGHPGDNR4A2 | |
| Formaldehyde SCHEMBL27873826 | 0.83 | RXRA (0.70) | RXRARXRBRXRGMRGPRX4ATM | |
| SCHEMBL8461702 | 0.82 | RXRA (0.70) | RXRARXRBRXRGHPGDNR4A2 | |
| SCHEMBL8460355 | 0.82 | RXRA (0.74) | RXRARXRBRXRGHPGDNR4A2 | |
| SCHEMBL8459307 | 0.82 | RXRA (0.69) | RXRARXRBRXRGHPGDNR4A2 | |
| SCHEMBL16823466 | 0.80 | RXRA (1.00) | RXRARXRBRXRGHPGDPTGER1 | |
| SCHEMBL8458553 | 0.79 | RXRA (0.65) | RXRARXRBRXRGHPGDNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| EP-0191735-B1 | NOVEL OXALURIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-09-12 | — | — | EP | claimed |
| EP-0191735-A2 | Novel oxaluric acid derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1986-08-20 | — | — | EP | claimed |
| US-20050245577-A1 | Drug for kidney failure containing oxaluric acid derivative | NIPPON ZOKI PHARMACEUTICALS CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1537866-A1 | DRUG FOR KIDNEY FAILURE CONTAINING OXALURIC ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co. Ltd. (JP) | 2005-06-08 | — | — | EP | disclosed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |
| EP-0191735-B1 | NOVEL OXALURIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4708954-A | DIABETES-ORAL ADMINISTRATION | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245577-A1 | Drug for kidney failure containing oxaluric acid derivative | OAT, OTC, OGFRL1 | RXRA 2718/4885RXRB 2921/4885RXRG 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.