Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214563 | 0.82 | LMNA (0.47) | LMNACCR5HKDC1TRPA1AOC3 | |
| SCHEMBL169508 | 0.76 | LMNA (0.56) | LMNACCR5HKDC1TRPA1AOC3 | |
| SCHEMBL21726134 | 0.76 | CCR5 (0.45) | LMNACCR5HKDC1TRPA1AOC3 | |
| SCHEMBL27254704 | 0.76 | CCR5 (0.45) | LMNACCR5HKDC1TRPA1AOC3 | |
| Hypochlorous Acid SCHEMBL11415854 | 0.74 | LMNA (0.56) | LMNACCR5HKDC1TRPA1AOC3 | |
| SCHEMBL15868611 | 0.74 | MAPT (0.44) | LMNACCR5MAPTCYP2D6GABBR2 | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.74 | LMNA (0.54) | LMNACCR5HKDC1TRPA1AOC3 | |
| SCHEMBL26341805 | 0.73 | LMNA (0.41) | LMNACCR5MAPTTAAR1CYP2D6 | |
| SCHEMBL6294907 | 0.73 | LMNA (0.41) | LMNACCR5HKDC1MAPTCYP2D6 | |
| SCHEMBL12566327 | 0.73 | LMNA (0.38) | LMNACCR5AOC3MAPTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975608-B1 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH INC (US) | 2005-06-15 | — | — | EP | disclosed |