Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852239 | 0.84 | KMT2A (0.44) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL6238073 | 0.71 | KMT2A (0.46) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL12928352 | 0.69 | GRM5 (0.42) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL12084055 | 0.68 | KMT2A (0.41) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL12086365 | 0.68 | ALDH1A1 (0.42) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL12510831 | 0.67 | HDAC4 (0.43) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL18419940 | 0.64 | KMT2A (0.45) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL6076551 | 0.64 | OPRM1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL352981 | 0.64 | HPGD (0.45) | HSD17B10HPGDKDM4ENPC1LMNA | |
| SCHEMBL12262039 | 0.64 | KMT2A (0.43) | HSD17B10HPGDKDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513843-A1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | Bayer CropScience AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000844-A1 | PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-12-31 | — | — | WO | disclosed |