SCHEMBL852239

SCHEMBL852239

Cc1cccc(C)c1N(C(=O)c1ccno1)C(C)(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
GAA P10253 4/20 0.36
GFER P55789 3/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 2/20 0.35
NPC1 O15118 2/20 0.35
HTT P42858 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RORC P51449 1/20 0.33
OPRM1 P35372 1/20 0.32
MEN1 O00255 1/20 0.32
PLA2G1B P04054 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238075 0.84 HSD17B10 (0.37) KMT2AGAAHSD17B10HPGDKDM4E
SCHEMBL6076551 0.80 OPRM1 (0.45) KMT2AKDM4ENPC1HTTRAB9A
SCHEMBL18419940 0.77 KMT2A (0.45) KMT2AGAAGFERHSD17B10HPGD
SCHEMBL7264107 0.77 KMT2A (0.45) KMT2AGAAGFERHSD17B10HPGD
SCHEMBL3423504 0.75 MEN1 (0.32) KMT2ANPC1HTTALDH1A1RAB9A
SCHEMBL394928 0.70 KMT2A (0.57) KMT2AGAAGFERHSD17B10HPGD
SCHEMBL394927 0.70 KMT2A (0.57) KMT2AGAAGFERHSD17B10HPGD
SCHEMBL3689800 0.70 ALDH1A1 (0.45) KMT2AHPGDTDP1LMNANPC1
SCHEMBL11408368 0.70 ALDH1A1 (0.33) KMT2AHSD17B10HPGDKDM4ETDP1
SCHEMBL12084055 0.70 KMT2A (0.41) KMT2AGAAGFERHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP claimed
EP-2533633-A2 FUNGICIDAL MIXTURES LANXESS Distribution GmbH (DE) 2012-12-19 EP claimed
WO-2011095492-A2 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-08-11 WO claimed
EP-2315522-A2 FORMATE-CONTAINING FUNGICIDE MIXTURES LANXESS Distribution GmbH (DE) 2011-05-04 EP claimed
WO-2010015635-A2 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2010-02-11 WO claimed
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP disclosed
EP-2233466-B1 4-Alkoxy-1-amino-1-cyclohexanecarboxylic acid derivatives and their use as intermediates BAYER IP GMBH (DE) 2015-06-10 EP disclosed
EP-2030969-B1 Spirocyclic 3-phenyl-3-substituted 4-ketolactams and 4-ketolactones BAYER IP GMBH (DE) 2015-03-18 EP disclosed
US-8916613-B2 Synergistic insecticidal mixtures BAYER CROPSCIENCE AG (DE) 2014-12-23 US disclosed
US-20140243326-A1 Synergistic Insecticidal Mixtures BAYER CROPSCIENCE AG (DE) 2014-08-28 US disclosed
EP-1830651-B1 INSECTICIDES BASED ON SELECTED NEONICOTINOIDS AND STROBILURINS BAYER CROPSCIENCE AG (DE) 2014-04-30 EP disclosed
EP-1533303-B1 Substituted Aminosalicylacid Amides ( intermediates ) BAYER CROPSCIENCE AG (DE) 2013-04-24 EP disclosed
WO-1998003495-A1 DIHYDROFURAN CARBOXAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-29 WO disclosed
WO-1998003486-A1 1,3-DIMETHYL-5-FLUORO-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-29 WO disclosed
WO-1997048280-A1 USE OF PYRROLOPYRIMIDINES TO COMBAT PESTS BAYER AKTIENGESELLSCHAFT (DE) 1997-12-24 WO disclosed
WO-1997047620-A1 N-SULFONYLIMIDAZOLES USED AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed
WO-1997047606-A1 ARYLOXYACRYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed
WO-1997047589-A1 AMINOPHTHALIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed
WO-1997026251-A1 ACYLATED 5-AMINO-1,2,4-THIADIAZOLES AS PESTICIDES AND FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-07-24 WO disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243326-A1 Synergistic Insecticidal Mixtures DDT, TBCB, PITPNB KMT2A 2899/4885GAA 4438/4885GFER 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.