SCHEMBL6238315

SCHEMBL6238315

CC=C(C)CCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
KEAP1 Q14145 1/20 0.52
FFAR1 O14842 1/20 0.48
TDP1 Q9NUW8 3/20 0.46
HDAC2 Q92769 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
GPR52 Q9Y2T5 1/20 0.44
KMT2A Q03164 1/20 0.44
TRPV1 Q8NER1 2/20 0.44
HDAC1 Q13547 2/20 0.43
HDAC3 O15379 1/20 0.43
MAPK1 P28482 1/20 0.43
ADRA1A P35348 1/20 0.43
HDAC4 P56524 1/20 0.43
SLC6A3 Q01959 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28754267 1.00 ALDH1A1 (0.59) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL5808516 0.88 FFAR1 (0.58) ALDH1A1FFAR1HDAC2HDAC1HTT
SCHEMBL20845697 0.83 ALDH1A1 (0.55) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL22375194 0.83 ALDH1A1 (0.55) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL20845698 0.83 ALDH1A1 (0.55) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL29408009 0.83 ALDH1A1 (0.55) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL4824729 0.83 ALDH1A1 (0.55) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL21486330 0.81 ALDH1A1 (0.53) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL29572084 0.81 ALDH1A1 (0.53) ALDH1A1KEAP1FFAR1TDP1HDAC2
SCHEMBL1977888 0.81 ALDH1A1 (0.53) ALDH1A1KEAP1FFAR1TDP1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005012222-A1 ALICYCLIC ESTER WITH MUSK FRAGRANCE SYMRISE GMBH & CO. KG (DE) 2005-02-10 WO disclosed
EP-0414207-A2 Method for preparing alpha-(-4-isobutylphenyl) propionic acid or its precursor NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-27 EP disclosed