Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572084 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TRPV1KEAP1TDP1FFAR1 | |
| SCHEMBL28415205 | 0.93 | TRPV1 (0.54) | ALDH1A1TRPV1KEAP1TDP1LSS | |
| SCHEMBL2813151 | 0.89 | FFAR1 (0.53) | ALDH1A1TRPV1FFAR1LSSHDAC2 | |
| SCHEMBL29408009 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TRPV1KEAP1TDP1FFAR1 | |
| SCHEMBL29105881 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TRPV1KEAP1TDP1FFAR1 | |
| SCHEMBL14672153 | 0.82 | FFAR1 (0.42) | ALDH1A1TDP1FFAR1MEN1CYP3A4 | |
| SCHEMBL8619944 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TRPV1KEAP1TDP1FFAR1 | |
| SCHEMBL8619950 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TRPV1KEAP1TDP1FFAR1 | |
| Geraniol SCHEMBL16245841 | 0.81 | KMT2A (0.59) | ALDH1A1TRPV1TDP1LSSMEN1 | |
| Geraniol SCHEMBL16245843 | 0.81 | KMT2A (0.59) | ALDH1A1TRPV1TDP1LSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908566-B1 | PREPARATION OF 5-ARYL PENTANOLS | BASF SE (DE) | 2023-07-26 | — | — | EP | disclosed |
| EP-3908566-A1 | PREPARATION OF 5-ARYL-PENTANOLS | BASF SE (DE) | 2021-11-17 | — | — | EP | disclosed |
| US-20210163456-A1 | CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| WO-2020144307-A1 | PREPARATION OF 5-ARYL-PENTANOLS | BASF SE (DE) | 2020-07-16 | — | — | WO | disclosed |
| WO-2019199667-A2 | CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE | KEANEY GREGG F (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163456-A1 | CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE | PLAAT5, PLAAT3, PLAAT4 | ALDH1A1 3225/4885TRPV1 4524/4885KEAP1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.