Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066614 | 0.89 | FFAR1 (0.70) | SRD5A2NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL402300 | 0.89 | SRD5A2 (0.87) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL4222632 | 0.87 | FFAR1 (0.68) | SRD5A2NR4A1NR4A2NR4A3MAOB | |
| Ammonia Solution, Strong SCHEMBL27788257 | 0.87 | FFAR1 (0.68) | SRD5A2NR4A1NR4A2NR4A3MAOB | |
| Hydrochloric Acid SCHEMBL10622121 | 0.87 | FFAR1 (0.68) | SRD5A2NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL3232949 | 0.87 | SRD5A2 (0.90) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL6182 | 0.87 | FFAR1 (0.69) | ALDH1A1HTTSRD5A2GAAMAPT | |
| SCHEMBL1744622 | 0.85 | FFAR1 (0.80) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL1415906 | 0.85 | SRD5A2 (0.73) | ALDH1A1HTTL3MBTL1SRD5A2GAA | |
| SCHEMBL8503301 | 0.84 | NR4A2 (0.74) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |