Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238431 | 0.90 | HPGD (0.53) | MAOBALKBH1MAPTALDH1A1GAA | |
| SCHEMBL2087289 | 0.84 | MAOB (0.70) | MAOBALDH1A1GAAMAOA | |
| SCHEMBL7031067 | 0.79 | LMNA (0.52) | MAOBPARP15PARP14PARP10LMNA | |
| SCHEMBL2087038 | 0.79 | NR4A2 (0.61) | MAOBPARP15PARP14PARP10ALKBH1 | |
| SCHEMBL6687945 | 0.78 | MAPT (0.58) | MAOBPARP15PARP14PARP10LMNA | |
| SCHEMBL6238440 | 0.77 | MAOB (0.74) | MAOBPARP10MAOA | |
| SCHEMBL19610706 | 0.77 | MET (0.53) | LMNAANO1MAPTGAA | |
| SCHEMBL6245446 | 0.76 | NR1H4 (0.47) | MAOBALKBH1 | |
| SCHEMBL2088021 | 0.76 | ALDH1A1 (0.59) | MAOBPARP15PARP14PARP10LMNA | |
| SCHEMBL7630628 | 0.75 | MMP1 (0.53) | LMNAALDH1A1GAAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |