Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240382 | 0.84 | AKR1C3 (0.48) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL6244432 | 0.80 | GRIK1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6242465 | 0.79 | MPO (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL6240932 | 0.78 | MPO (0.45) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24193545 | 0.73 | LMNA (0.55) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL6245588 | 0.71 | HPGD (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL27728396 | 0.71 | MEN1 (0.51) | ALDH1A1HSD17B10NPSR1MEN1KMT2A | |
| SCHEMBL6238605 | 0.68 | CMA1 (0.40) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL6647328 | 0.67 | LCK (0.56) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL20745310 | 0.67 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023238-A1 | ERG CHANNEL OPENERS FOR THE TREATMENT OF HYPEREXCITABILITY-RELATED NEURONAL DISEASES | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-03-17 | — | — | WO | claimed |