Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728396 | 0.85 | MEN1 (0.51) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6240382 | 0.80 | AKR1C3 (0.48) | LMNASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL16518675 | 0.80 | MAPT (0.61) | LMNASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL24193445 | 0.76 | CA1 (0.43) | LMNASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL24193627 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL6250057 | 0.75 | HSD17B10 (0.43) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL10434328 | 0.73 | TSHR (0.54) | LMNASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL6238617 | 0.73 | KDM4E (0.53) | LMNASMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL5074252 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1GAARAB9ANPC1 | |
| SCHEMBL19427499 | 0.72 | NPC1 (0.63) | SMN1; SMN2ALDH1A1GAAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220009900-A1 | N-TRIFLUORMETHYLCARBONYL COMPOUNDS AND METHODS FOR THEIR SYNTHESIS | RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009900-A1 | N-TRIFLUORMETHYLCARBONYL COMPOUNDS AND METHODS FOR THEIR SYNTHESIS | SCLY, NNMT, NPM1 | LMNA 2493/4885SMN1; SMN2 2105/4885ALDH1A1 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.