Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737432 | 0.81 | KDM5B (0.30) | KDM5B | |
| SCHEMBL10704444 | 0.78 | ALDH1A1 (0.33) | ALDH1A1ALOX15TSHRATF1NFKB1 | |
| SCHEMBL219104 | 0.76 | ALDH1A1 (0.47) | ALDH1A1ALOX15TSHR | |
| SCHEMBL19024150 | 0.74 | ATF1 (0.33) | ALDH1A1ALOX15TSHRATF1NFKB1 | |
| SCHEMBL12599916 | 0.69 | HSP90AA1 (0.33) | — | |
| SCHEMBL5635013 | 0.69 | ALDH1A1 (0.39) | ALDH1A1ALOX15TSHR | |
| SCHEMBL15218852 | 0.67 | TSHR (0.35) | ALDH1A1ALOX15TSHR | |
| SCHEMBL10703268 | 0.67 | — | — | |
| SCHEMBL3533585 | 0.66 | ENPP3 (0.30) | — | |
| SCHEMBL31224694 | 0.65 | ALDH1A1 (0.30) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019207-A1 | FUNGICIDAL PYRIMIDINE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-03-03 | — | — | WO | disclosed |
| US-20050038041-A1 | Fungicidal pyrimidine derivatives | NIPPON SODA CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-6818631-B1 | 4-FLUOROALKYL SUBSTITUENT; AGRICULTURE, HORTICULTURE; PLANT DISEASE CONTROL | NIPPON SODA CO. LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
| US-4716229-A | New pyrimidines and a process for the preparation of pyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0133663-B1 | PYRIMIDINES AND A PROCESS FOR THE PREPARATION OF PYRIMIDINES | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| EP-0133663-A1 | Pyrimidines and a process for the preparation of pyrimidines | BAYER AG (DE) | 1985-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038041-A1 | Fungicidal pyrimidine derivatives | CBR3, CBR1, TH | ALDH1A1 1037/4885ALOX15 3968/4885TSHR 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.