SCHEMBL5635013

SCHEMBL5635013

Fc1nc(Cl)nc(Cl)c1F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219104 0.84 ALDH1A1 (0.47) ALDH1A1ALOX15TSHR
SCHEMBL1598822 0.84 ALDH1A1 (0.47) ALDH1A1ALOX15TSHR
SCHEMBL9471045 0.77 ALDH1A1 (0.39) ALDH1A1ALOX15TSHR
SCHEMBL8581211 0.77
SCHEMBL4048252 0.73
SCHEMBL8635855 0.72
SCHEMBL30166648 0.72 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL30861998 0.72 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL15444652 0.72 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL20267103 0.72 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776014-A Tobacco continuous cropping soil regulator and preparation method thereof 台沃科技集团股份有限公司 2025-04-08 CN disclosed
US-8580802-B2 Pyrrolo[2,3-D]pyrimidines as inhibitors of Janus kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-11-12 US disclosed
US-20070207995-A1 Deazapurines useful as inhibitors of Janus kinases VERTEX PHARMACEUTICALS INCORPORATED 2007-09-06 US disclosed
US-5463031-A Printing, dyeing cellulose and organonitrogen compounds BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
US-5233105-A Fluorination using hydrogen fluoride BAYER AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
US-4161593-A Process for the preparation of triazines containing a mixture of chlorine and fluorine substituents, and of cyanuric fluoride BAYER AKTIENGESELLSCHAFT (DE) 1979-07-17 US disclosed
US-4052386-A REACTIVE PHTHALOCYANINE DYESTUFFS CONTAINING A FLUOROPYRIMIDINYL GROUP BAYER AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207995-A1 Deazapurines useful as inhibitors of Janus kinases JAK1, JAK3, JAK2 ALDH1A1 2028/4885ALOX15 2548/4885TSHR 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.