SCHEMBL6238770

SCHEMBL6238770

CCC#CCOc1cc(N)c(Cl)cc1C(=O)NC1C2COCC1CN(C)C2

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.49
ADRA2B P18089 1/20 0.49
ADRA2C P18825 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
HTR3A P46098 5/20 0.46
HTR4 Q13639 2/20 0.44
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR5A P47898 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
MEN1 O00255 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6237211 0.94 ADRA2A (0.51) ADRA2AADRA2BADRA2CHTR2AHTR2C
SCHEMBL6234223 0.94 ADRA2A (0.50) ADRA2AADRA2BADRA2CHTR2AHTR2C
Hydrochloric Acid SCHEMBL6232454 0.93 ADRA2A (0.49) ADRA2AADRA2BADRA2CHTR2AHTR2C
SCHEMBL6235633 0.84 HTR4 (0.60) HTR4
SCHEMBL6232466 0.84 HTR4 (0.60) HTR4
SCHEMBL6266458 0.84 ADRA2A (0.48) ADRA2AADRA2BADRA2CHTR2AHTR2C
Hydrochloric Acid SCHEMBL6232972 0.84 HTR4 (0.59) HTR4
Hydrochloric Acid SCHEMBL6268711 0.83 ADRA2A (0.47) ADRA2AADRA2BADRA2CHTR2AHTR2C
SCHEMBL6232600 0.81 DRD4 (0.56) ADRA2AADRA2BADRA2CHTR2AHTR2C
Hydrochloric Acid SCHEMBL6236267 0.80 DRD4 (0.55) ADRA2AADRA2BADRA2CHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005007600-A2 NOVEL METHODS USING AMINOBENZOIC ACID COMPOUNDS EISAI CO., LTD. (JP) 2005-01-27 WO disclosed