SCHEMBL6238817

SCHEMBL6238817

CCCCC(NC(CCCC)C(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.52
MAPK1 P28482 1/20 0.52
NOD1 Q9Y239 3/20 0.50
GPR84 Q9NQS5 3/20 0.45
FFAR1 O14842 1/20 0.45
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
ACE P12821 1/20 0.43
MAPT P10636 1/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
HDAC2 Q92769 2/20 0.43
CHRM1 P11229 1/20 0.42
AKR1A1 P14550 1/20 0.42
CHRM3 P20309 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11220090 0.91 GPR84 (0.57) NOD1GPR84FFAR1ACEMAPT
SCHEMBL17024089 0.91 GPR84 (0.57) NOD1GPR84FFAR1ACEMAPT
SCHEMBL3898059 0.89 CA2 (0.47) CA2MAPK1NOD1GPR84FFAR1
SCHEMBL13392452 0.89 CA2 (0.47) CA2MAPK1NOD1GPR84FFAR1
SCHEMBL5869797 0.88 PLA2G2A (0.51) CA2MAPK1NOD1SLC1A3SLC1A2
SCHEMBL8248644 0.88 PLA2G2A (0.51) CA2MAPK1NOD1SLC1A3SLC1A2
SCHEMBL22745777 0.86 CA2 (0.48) CA2MAPK1NOD1GPR84ACE
SCHEMBL10735795 0.85 CHRM1 (0.52) CA2MAPK1NOD1GPR84SLC1A3
SCHEMBL429475 0.84 CA2 (0.50) CA2MAPK1NOD1GPR84FFAR1
SCHEMBL201058 0.84 CA2 (0.50) CA2MAPK1NOD1GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4642221-A AROMATIC TRIAZOLES AND IMINODICARBOXYLIC ACID DERIVATIVES ATLANTIC RICHFIELD COMPANY (US) 1987-02-10 US claimed
EP-1124881-B1 CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES INVISTA TECH SARL (US) 2005-04-27 EP disclosed
US-6815527-B2 REACTING AMINONITRILE WITH WATER IN ORGANIC LIQUID DILUENT AT ELEVATED TEMPERATURE AND PRESSURE IN FLOW TUBE WITH SELECTED BRONSTED ACID CATALYST, FURTHER REACTING TO FORM AND SEPARATE GAS PHASE, MIXING REMAINDER WITH WATER TO FORM PRODUCT BASF AKTIENGESELLSCHAFT (DE) 2004-11-09 US disclosed
US-20040102604-A1 Continuous method fore producing polyamides from aminonitriles BASF AKTIENGESELLSCHAFT (DE) 2004-05-27 US disclosed
EP-1335897-A1 PRODUCTION OF 6-AMINOCAPROIC ACID INVISTA Technologies S.à.r.l. (US) 2003-08-20 EP disclosed
WO-2002040440-A1 PRODUCTION OF 6-AMINOCAPROIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-05-23 WO disclosed
US-6372939-B1 HYDROFORMYLATING 3-PENTENENITRILE IN PRESENCE OF CATALYST COMPRISING GROUP VIII ELEMENT TO PRODUCE MIXTURE OF FORMYLVALERONITRILES, OXIDIZING TO CYANOVALERIC ACIDS, CATALYTICALLY HYDROGENATING TO 6-AMINOCAPROIC ACID AND ISOMERS E.I. DU PONT DE NEMOURS AND COMPANY 2002-04-16 US disclosed
EP-1124881-A1 CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-08-22 EP disclosed
US-6201096-B1 SUCH AS 6-AMINOCAPRONITRILE, WHICH IS INTRODUCED AT THE TOP OF A VERTICAL MULTISTAGE REACTOR BEING SWEPT COUNTERCURRENTLY WITH STEAM AND POLYAMIDE SUCH AS NYLON 6 IS RECOVERED NEAR THE BOTTOM OF THE REACTOR; LOW UNREACTED NITRILE END GROUPS E. I. DU PONT DE NEMOURS AND COMPANY 2001-03-13 US disclosed
WO-2000024808-A1 CONTINUOUS POLYMERIZATION PROCESS FOR PREPARING POLYAMIDES FROM OMEGA-AMINONITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-04 WO disclosed