Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212728 | 0.85 | DHODH (0.44) | DHODHALDH1A1MAPTKMT2AESR1 | |
| SCHEMBL3576266 | 0.81 | KDM4E (0.46) | DHODHALDH1A1MAPTKMT2AESR1 | |
| SCHEMBL1340553 | 0.79 | MAPT (0.63) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL30395267 | 0.79 | DHODH (0.60) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL121400 | 0.78 | DHODH (0.94) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL30444259 | 0.77 | DHODH (0.57) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL30444341 | 0.76 | DHODH (0.56) | DHODHALDH1A1MAPTKMT2AESR1 | |
| SCHEMBL4310699 | 0.76 | DHODH (0.56) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL30444482 | 0.76 | DHODH (0.56) | DHODHALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL505539 | 0.76 | DHODH (1.00) | DHODHALDH1A1ESR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021248-A | SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | claimed |
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115124485-A | Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof | 中国医学科学院药物研究所 | 2022-09-30 | — | — | CN | disclosed |
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6797717-B2 | ACYL COENZYME A CHOLESTEROL ACYLTRANSFERASE (ACAT) INHIBITORS | KOWA COMPANY, LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD., JAPAN | 2003-05-08 | — | — | US | disclosed |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | KOWA COMPANY, LTD.,JAPAN | 2002-07-25 | — | — | US | disclosed |
| US-6362208-B1 | ANTICHOLESTEROL AGENT | KOWA COMPANY, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1020451-A1 | NOVEL ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0377889-B1 | Silver halide recording material | AGFA GEVAERT AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0373339-B1 | Silver halide recording material | AGFA GEVAERT AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5089381-A | SILVER HALIDE RECORDING MATERIAL | AGFA-GEVAERT AG (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0377889-A1 | Silver halide recording material | Agfa-Gevaert AG (DE) | 1990-07-18 | — | — | EP | disclosed |
| EP-0373339-A1 | Silver halide recording material | Agfa-Gevaert AG (DE) | 1990-06-20 | — | — | EP | disclosed |
| US-4021248-A | SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087928-A1 | Novel anilide compounds and drugs containing the same | ACAT1, ACAT2, LCAT | DHODH 373/4885ALDH1A1 211/4885NR4A1 1814/4885 |
| US-20020099074-A1 | Novel anilide compounds and drugs containing the same | SOAT1, SOAT2, LCAT | DHODH 455/4885ALDH1A1 236/4885NR4A1 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.