SCHEMBL6239157

SCHEMBL6239157

CCCCCCCC[CH]C(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
THRB P10828 1/20 0.44
FAAH O00519 2/20 0.42
TRPV1 Q8NER1 1/20 0.42
DNM1 Q05193 4/20 0.41
EP300 Q09472 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9204861 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL410012 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4140881 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4023020 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL5323261 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9205872 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL6984187 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9206806 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL6246240 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL8080093 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237311-A1 LOW DIELECTRIC CONSTANT, LOW DIELECTRIC DISSIPATION FACTOR COATINGS, FILMS AND ADHESIVES MIZORI FARHAD G (US) 2016-08-18 US claimed
WO-2015048575-A1 LOW DIELECTRIC CONSTANT, LOW DIELECTRIC DISSIPATION FACTOR COATINGS, FILMS AND ADHESIVES DESIGNER MOLECULES, INC. (US) 2015-04-02 WO claimed
EP-0748357-B1 AMINO AND FLUORO GROUP CONTAINING SILOXANES DU PONT (US) 1999-06-16 EP claimed
EP-4013385-B1 IMPROVED LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS ACUITAS THERAPEUTICS INC (CA) 2024-07-03 EP disclosed
US-20240158458-A1 MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF MODERNA TX INC (US) 2024-05-16 US disclosed
US-11969506-B2 Lipid nanoparticle formulation MODERNATX, INC. (US) 2024-04-30 US disclosed
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2024-04-18 US disclosed
US-20240024422-A1 POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2024-01-25 US disclosed
EP-3458105-B1 POLYNUCLEOTIDES ENCODING GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FOR THE TREATMENT OF GALACTOSEMIA TYPE 1 MODERNATX INC (US) 2024-01-17 EP disclosed
CN-117224710-A Immunomodulatory therapeutic MRNA compositions encoding mutant peptides that activate oncogenes 莫得纳特斯公司 2023-12-15 CN disclosed
EP-4286012-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2023-12-06 EP disclosed
EP-0889097-A1 PHTHALOCYANINE COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND OPTICAL RECORDING MEDIUM MADE USING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 1999-01-07 EP disclosed
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
US-4737297-A MONO-SUBSTITUTED NAPHTHALENES NIPPON OIL CO., LTD. (JP) 1988-04-12 US disclosed
US-4665275-A OXIDATION-RESISTANT NAPHTHALENE DERIVATIVE NIPPON OIL CO., LTD. (JP) 1987-05-12 US disclosed
EP-0209990-A2 Thermal transfer printing IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11969506-B2 Lipid nanoparticle formulation TTPA, SREBF1, SREBF2 TSHR 1913/4885THRB 1782/4885FAAH 2258/4885
US-20240024422-A1 POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF IL2, IL15, RBM12 TSHR 3940/4885THRB 4329/4885FAAH 4084/4885
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 TSHR 3089/4885THRB 3096/4885FAAH 3137/4885
US-20240158458-A1 MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF IL2, LCP2, IFNG TSHR 1274/4885THRB 2469/4885FAAH 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.