SCHEMBL6239200

SCHEMBL6239200

O=C(O)COC(=O)CNc1cccc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.47
MEN1 O00255 8/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 6/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
HTT P42858 3/20 0.46
LMNA P02545 2/20 0.46
RXFP1 Q9HBX9 1/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.44
GRK2 P25098 3/20 0.43
GRK3 P35626 2/20 0.43
ROCK2 O75116 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
GRK5 P34947 1/20 0.43
KYAT1 Q16773 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5287728 0.84 MAPT (0.54) KMT2AMEN1GAAMAPTNPC1
Hydrochloric Acid SCHEMBL30605752 0.82 MEN1 (0.56) KMT2AMEN1GAAMAPTNPC1
SCHEMBL30421886 0.82 MEN1 (0.56) KMT2AMEN1GAAMAPTNPC1
Hydrochloric Acid SCHEMBL28590040 0.82 MEN1 (0.56) KMT2AMEN1GAAMAPTNPC1
SCHEMBL157003 0.82 MEN1 (0.56) KMT2AMEN1GAAMAPTNPC1
SCHEMBL11729327 0.82 MEN1 (0.51) KMT2AMEN1GAAMAPTNPC1
SCHEMBL7593370 0.81 MEN1 (0.51) KMT2AMEN1GAAMAPTNPC1
Hydrochloric Acid SCHEMBL15646288 0.80 MEN1 (0.50) KMT2AMEN1GAAMAPTNPC1
SCHEMBL6243149 0.79 MEN1 (0.51) KMT2AMEN1GAAMAPTNPC1
Cadaverine Tartrate SCHEMBL28777306 0.77 HPGD (0.46) KMT2AMEN1GAAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539492-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES Kodak Polychrome Graphics, LLC (US) 2005-06-15 EP disclosed
WO-2004014652-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2004-02-19 WO disclosed