Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | GRK3 | P35626 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243396 | 0.84 | CYP19A1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL23771128 | 0.82 | MTNR1A (0.56) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL7593370 | 0.81 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11667343 | 0.81 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL15646288 | 0.80 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6239200 | 0.79 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL30421886 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL157003 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL30605752 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL28590040 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-B1 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL INC (US) | 2005-06-29 | — | — | EP | disclosed |