SCHEMBL623922

SCHEMBL623922

CCCC[C]1C(=O)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.36
ALDH1A1 P00352 4/20 0.36
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33
DAO P14920 1/20 0.33
SCD O00767 1/20 0.33
DUSP3 P51452 1/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
CTRC Q99895 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8231769 0.80 TP53 (0.38) TYMPALDH1A1DAOCYP1A2CYP2C9
SCHEMBL4611630 0.72 CDC25A (0.44) ALDH1A1ACHEBACE1SCDMAPT
SCHEMBL13281066 0.67 SCD (0.45) TYMPALDH1A1ACHEBACE1SCD
SCHEMBL13280457 0.67 SCD (0.45) TYMPALDH1A1ACHEBACE1SCD
SCHEMBL320624 0.65 SCD (0.54) ALDH1A1SCDCES2CES1THRB
SCHEMBL9276218 0.65
SCHEMBL7739728 0.64 ALDH1A1 (0.32) ALDH1A1DAOSCDGAAMAPT
SCHEMBL6361888 0.63 STAT3 (0.58) ALDH1A1ACHEBACE1DAOMAPT
SCHEMBL6053940 0.63 TSHR (0.35) THRBHPGD
SCHEMBL3411557 0.63 TYMP (0.45) TYMPALDH1A1DAOCTRCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP claimed
EP-4168566-A1 METHODS FOR PRODUCING BIOTIN IN GENETICALLY MODIFIED MICROORGANISMS Biosyntia ApS (DK) 2023-04-26 EP claimed
WO-2023285585-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2023-01-19 WO claimed
CN-114480513-A Method for synthesizing muscone in vitro by gene editing yeast 北京林业大学 2022-05-13 CN claimed
WO-2021254927-A1 METHODS FOR PRODUCING BIOTIN IN GENETICALLY MODIFIED MICROORGANISMS BIOSYNTIA APS (DK) 2021-12-23 WO claimed
US-6475751-B2 Scintillation proximity assay for type II fatty acid biosynthetic enzymes VIRGINIA COMMONWEALTH UNIVERSITY 2002-11-05 US claimed
US-20010031477-A1 Scintillation proximity assay for type II fatty acid biosynthetic enzymes VIRGINIA COMMONWEALTH UNIVERSITY 2001-10-18 US claimed
WO-2001051925-A1 A SCINTILLATION PROXIMITY ASSAY FOR TYPE II FATTY ACID BIOSYNTHETIC ENZYMES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2001-07-19 WO claimed
US-12031167-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2024-07-09 US disclosed
WO-2024132882-A1 LIPID PRODUCING MARINE MICROALGA HUTANBIO LTD. (GB) 2024-06-27 WO disclosed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP disclosed
CN-117965408-A Production of acyl amino acids 模块遗传学公司 2024-05-03 CN disclosed
CN-117897476-A Microbial cell factory for producing vitamin B compounds 拜奥信尼亚私营有限责任公司 2024-04-16 CN disclosed
US-20240060100-A1 PROCESSES FOR PRODUCTION OF ALKYLATED FATTY ACIDS AND DERIVATIVES THEREOF ExxonMobil Technology and Engineering Company 2024-02-22 US disclosed
WO-2001030752-A2 INDOLE COMPOUNDS FOR TREATING BACTERIAL INFECTIONS SMITHKLINE BEECHAM CORPORATION (US) 2001-05-03 WO disclosed
WO-2001030775-A1 NOVEL INDOLE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2001-05-03 WO disclosed
EP-0986296-A1 FATTY ACID ELONGASES Cargill Incorporated (US) 2000-03-22 EP disclosed
WO-1998054954-A9 FATTY ACID ELONGASES CARGILL INC (US) 1999-04-08 WO disclosed
WO-1998054954-A1 FATTY ACID ELONGASES CARGILL, INCORPORATED (US) 1998-12-10 WO disclosed
US-5445952-A Transformed Escherichia coli cell which can produce biotin in culture BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12031167-B2 Generation of acyl amino acids FADS1, FADS2, FAR1 TYMP 1877/4885ALDH1A1 1637/4885ACHE 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.