SCHEMBL623927

SCHEMBL623927

COc1ccc(-c2cnc3sc(NC4CCN(S(C)(=O)=O)CC4)nn23)cc1OC

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FYN P06241 19/20 0.72
HASPIN Q8TF76 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1946299 0.85 FYN (0.81) FYNHASPIN
SCHEMBL2255821 0.84 FYN (0.78) FYNHASPIN
SCHEMBL1945921 0.84 FYN (1.00) FYNHASPIN
SCHEMBL624430 0.83 FYN (0.72) FYNHASPIN
SCHEMBL623928 0.81 FYN (0.49) FYN
SCHEMBL626171 0.80 FYN (0.54) FYNHASPIN
SCHEMBL626186 0.79 FYN (0.51) FYNHASPIN
SCHEMBL626164 0.77 FYN (0.51) FYNHASPIN
SCHEMBL627167 0.77 FYN (0.46) FYNHASPIN
SCHEMBL27794654 0.76 FYN (0.73) FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020217-A1 AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) 2012-02-16 WO disclosed