Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 13/20 | 0.51 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626171 | 0.87 | FYN (0.54) | FYNHASPINKCNH2 | |
| SCHEMBL624430 | 0.84 | FYN (0.72) | FYNHASPIN | |
| SCHEMBL626164 | 0.84 | FYN (0.51) | FYNHASPINKCNH2CCR6 | |
| SCHEMBL626187 | 0.82 | JAK3 (0.38) | FYNJAK3CCR6TNF | |
| SCHEMBL623927 | 0.79 | FYN (0.72) | FYNHASPIN | |
| SCHEMBL626206 | 0.77 | PIK3CA (0.53) | FYNHASPIN | |
| SCHEMBL627167 | 0.76 | FYN (0.46) | FYNHASPINKCNH2JAK3 | |
| SCHEMBL624393 | 0.75 | FYN (0.46) | FYNHASPIN | |
| SCHEMBL626703 | 0.74 | PIK3CA (0.53) | FYNHASPIN | |
| SCHEMBL625476 | 0.71 | FYN (0.73) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |