Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.58 |
| ▸ | HNF4A | P41235 | 9/20 | 0.58 |
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242408 | 0.83 | RXRA (0.59) | RXRAHNF4ARARG | |
| SCHEMBL6269934 | 0.80 | RXRA (0.59) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6242411 | 0.77 | RXRA (0.50) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6239279 | 0.77 | RXRA (0.58) | RXRAHNF4ARARGRARB | |
| SCHEMBL6239175 | 0.77 | RXRA (0.67) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6914152 | 0.74 | RXRA (1.00) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6240335 | 0.72 | RXRA (0.56) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6240826 | 0.71 | RXRA (0.58) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL6239181 | 0.71 | RXRA (0.55) | RXRAHNF4ARARGRARBRXRG | |
| SCHEMBL22394641 | 0.71 | LMNA (0.43) | RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |