SCHEMBL6239375 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HNF4A	P41235	8/20	0.49

▸	RXRA	P19793	12/20	0.46

▸	RARB	P10826	8/20	0.41

▸	RARG	P13631	8/20	0.41

▸	RARA	P10276	6/20	0.40

▸	RXRB	P28702	2/20	0.39

▸	RXRG	P48443	2/20	0.39

▸	HCRTR1	O43613	1/20	0.36

▸	HCRTR2	O43614	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6239783	0.81	HNF4A (0.72)	HNF4ARXRARARBRARGRARA
SCHEMBL6239181	0.78	RXRA (0.55)	HNF4ARXRARARBRARGRARA
SCHEMBL6273432	0.77	HNF4A (0.57)	HNF4ARXRARARBRARGRARA
SCHEMBL6239175	0.75	RXRA (0.67)	HNF4ARXRARARBRARGRARA
SCHEMBL6240826	0.72	RXRA (0.58)	HNF4ARXRARARBRARGRARA
SCHEMBL6240820	0.71	RXRA (0.49)	HNF4ARXRARARBRARGRARA
SCHEMBL6273701	0.71	HNF4A (0.60)	HNF4ARXRARARBRARGRARA
SCHEMBL6243135	0.70	RXRA (0.53)	HNF4ARXRARARBRARGRARA
SCHEMBL6239279	0.70	RXRA (0.58)	HNF4ARXRARARBRARGRARA
SCHEMBL6243129	0.68	RXRA (0.55)	HNF4ARXRARARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2005017185-A2	HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS	LIGAND PHARMCEUTICALS INCORPORATED (US)	2005-02-24	—	—	WO	disclosed