Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689086 | 0.81 | — | — | |
| SCHEMBL205085 | 0.81 | TSHR (0.36) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL231825 | 0.78 | TSHR (0.38) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL17102755 | 0.77 | ALDH1A1 (0.33) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL31302757 | 0.73 | SMN1; SMN2 (0.35) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL235489 | 0.73 | ALDH1A1 (0.35) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL30260080 | 0.73 | ALDH1A1 (0.35) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL31302767 | 0.73 | SMN1; SMN2 (0.35) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL4217051 | 0.73 | MMP1 (0.31) | TSHRALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL19973300 | 0.73 | ALDH1A1 (0.31) | TSHRALDH1A1TP53HSP90AA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019233579-A1 | ORGANOPOLYSILOXANES THAT CROSS-LINK AT ROOM TEMPERATURE | WACKER CHEMIE AG (DE) | 2019-12-12 | — | — | WO | disclosed |
| EP-2820025-B1 | CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2016-02-17 | — | — | EP | disclosed |
| EP-2789656-B1 | Crosslinkable compositions based on organosilicon compounds | WACKER CHEMIE AG (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-8987373-B2 | Crosslinkable compositions based on organosilicon compounds | WACKER CHEMIE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20140309370-A1 | CROSSLINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2014-10-16 | — | — | US | disclosed |
| EP-2789656-A1 | Crosslinkable compositions based on organosilicon compounds | Wacker Chemie AG (DE) | 2014-10-15 | — | — | EP | disclosed |
| EP-1008149-B1 | ELECTROCONDUCTIVE COMPOSITION, COMPOSITE SUITABLE FOR MAKING SAME, AND METHODS FOR PRODUCING SUCH COMPOSITION AND COMPOSITE | POTTERS INDUSTRIES INC (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2005028486-A1 | METHODS OF REFINING SILANE COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2005-03-31 | — | — | WO | disclosed |
| US-20050059835-A1 | Methods of refining silane compounds | HONEYWELL INTERNATIONAL INC. (US) | 2005-03-17 | — | — | US | disclosed |
| US-6241914-B1 | Electroconductive composition composite suitable for making same and methods for producing such composition and composite | POTTERS INDUSTRIES, INC. | 2001-06-05 | — | — | US | disclosed |
| US-4399267-A | AMINE- OR OXIME-CONTAINING SILANE, MERCAPTOALKYLSILANE, SCREEN PRINTING | WACKER-CHEMIE GMBH (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0073446-A1 | Silicone rubber with retarded skin-forming properties | Wacker-Chemie GmbH (DE) | 1983-03-09 | — | — | EP | disclosed |
| EP-0000929-B1 | POLYSILOXANES BASED COMPOSITIONS CONVERTIBLE INTO ELASTOMERS BY CROSS-LINKING | Wacker-Chemie GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |
| US-4211729-A | Compositions containing diorganopolysiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE, GMBH (DE) | 1980-07-08 | — | — | US | disclosed |
| US-4191817-A | POLYSILOXANE WITH AMINOALKYL GROUP, AMINOSILANE OR OXIMOSILANE | WACKER-CHEMIE GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-4170700-A | AMINO-SILICON COMPOUND, CARBON DIOXIDE | SWS SILICONES CORPORATION (US) | 1979-10-09 | — | — | US | disclosed |
| US-4147855-A | PHOSPHATE NITROGEN-CONTAINING HYDROLYZABLE SILANE | WACKER-CHEMIE GMBH (DE) | 1979-04-03 | — | — | US | disclosed |
| EP-0000929-A1 | Polysiloxanes based compositions convertible into elastomers by cross-linking | Wacker-Chemie GmbH (DE) | 1979-03-07 | — | — | EP | disclosed |
| US-4072655-A | Organosilicon compounds as additives for curable organopolysiloxane compositions | WACKER-CHEMIE GMBH (DT) | 1978-02-07 | — | — | US | disclosed |
| US-4026853-A | Curable bituminous organopolysiloxane compositions | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059835-A1 | Methods of refining silane compounds | HDAC10, HDAC1, HDAC11 | TSHR 3353/4885ALDH1A1 1608/4885TP53 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.