Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.47 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.47 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.47 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237490 | 0.84 | ABCG2 (0.67) | ABCG2EGFRMEN1KMT2AMAPT | |
| SCHEMBL6232602 | 0.83 | ABCG2 (0.55) | ABCG2EGFRMEN1KMT2AMAPT | |
| SCHEMBL7691382 | 0.82 | ABCG2 (0.61) | ABCG2EGFRMEN1KMT2AMAPT | |
| SCHEMBL6237367 | 0.76 | CYP1A2 (0.51) | ABCG2GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL17597920 | 0.74 | GUCY1B2 (0.73) | ABCG2EGFRRHOAGUCY1B2GUCY1A2 | |
| SCHEMBL19129480 | 0.72 | GUCY1B2 (0.77) | ABCG2EGFRRHOAGUCY1B2GUCY1A2 | |
| SCHEMBL7697772 | 0.72 | RPS6KB2 (0.58) | ABCG2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17598175 | 0.71 | GUCY1B2 (0.76) | ABCG2EGFRRHOAGUCY1B2GUCY1A2 | |
| SCHEMBL20299204 | 0.71 | ABCG2 (0.72) | ABCG2EGFRMEN1KMT2AMAPT | |
| SCHEMBL22860661 | 0.71 | EGFR (0.67) | ABCG2EGFRRHOAGUCY1B2GUCY1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007099-A2 | PKB INHIBITORS AS ANTI-TUMOR AGENTS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-27 | — | — | WO | disclosed |