Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237490 | 0.89 | ABCG2 (0.67) | ABCG2EGFRAURKBRAB9AMAPT | |
| SCHEMBL7691382 | 0.87 | ABCG2 (0.61) | ABCG2EGFRAURKBRAB9AMAPT | |
| SCHEMBL6239581 | 0.83 | ABCG2 (0.54) | ABCG2EGFRAURKBMAPTSMN1; SMN2 | |
| SCHEMBL6237894 | 0.78 | RPS6KB2 (0.64) | RAB9AMAPTSMN1; SMN2RPS6KB2KDM4E | |
| SCHEMBL6235369 | 0.75 | MEN1 (0.58) | ABCG2EGFRMAPTRPS6KB2CSNK2A1 | |
| SCHEMBL6236522 | 0.75 | ABCG2 (0.48) | ABCG2EGFRMAPTRPS6KB2CSNK2A1 | |
| SCHEMBL6259663 | 0.75 | PDE5A (0.61) | ABCG2RAB9AMAPTSMN1; SMN2RPS6KB2 | |
| SCHEMBL6239609 | 0.74 | MAPT (0.51) | ABCG2EGFRMAPTCSNK2A1TP53 | |
| SCHEMBL7697772 | 0.74 | RPS6KB2 (0.58) | ABCG2MAPTSMN1; SMN2RXFP1RPS6KB2 | |
| SCHEMBL11932222 | 0.73 | CSNK2A1 (0.71) | EGFRCSNK2A1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007099-A2 | PKB INHIBITORS AS ANTI-TUMOR AGENTS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-27 | — | — | WO | disclosed |