Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | VDR | P11473 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857028 | 0.89 | L3MBTL1 (0.62) | PPARDFFAR1FFAR4L3MBTL1PTGER4 | |
| SCHEMBL6239053 | 0.82 | FFAR1 (0.75) | FFAR1FFAR4PTGER4 | |
| SCHEMBL6241283 | 0.80 | FFAR4 (0.78) | FFAR1FFAR4 | |
| SCHEMBL6237904 | 0.79 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL6239954 | 0.79 | NR1H4 (0.56) | FFAR1FFAR4THRATHRB | |
| SCHEMBL6237724 | 0.78 | MAOB (0.64) | PPARDFFAR1FFAR4PTGER4THRA | |
| SCHEMBL6963905 | 0.78 | L3MBTL1 (0.73) | FFAR1L3MBTL1RXRA | |
| SCHEMBL4207640 | 0.78 | SLC13A5 (0.60) | PPARDFFAR1PTGER4RXRAPPARG | |
| SCHEMBL5204454 | 0.77 | PTGDR2 (0.53) | — | |
| SCHEMBL28141293 | 0.76 | AKR1B1 (0.58) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |