SCHEMBL6237904

SCHEMBL6237904

O=C(O)Cc1ccc(OCc2ccccc2-c2cc(F)ccc2F)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.57
FFAR4 Q5NUL3 17/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241283 0.84 FFAR4 (0.78) FFAR1FFAR4
SCHEMBL3500758 0.81 MAOB (0.63) FFAR1FFAR4
SCHEMBL9890682 0.80 CXCL8 (0.50)
SCHEMBL6239053 0.79 FFAR1 (0.75) FFAR1FFAR4
SCHEMBL6239647 0.79 PPARD (0.61) FFAR1FFAR4
SCHEMBL6239954 0.78 NR1H4 (0.56) FFAR1FFAR4
SCHEMBL6241934 0.76 POLB (0.56) FFAR1FFAR4
SCHEMBL10566317 0.76 FFAR4 (0.52) FFAR1FFAR4
SCHEMBL10565772 0.76 RXRA (0.51) FFAR1FFAR4
SCHEMBL6240357 0.75 FFAR4 (0.47) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005009104-A2 BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS LIGAND PHARMACUETICALS INCORPORATED (US) 2005-02-03 WO claimed
WO-2005009104-A2 BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS LIGAND PHARMACUETICALS INCORPORATED (US) 2005-02-03 WO disclosed