Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759812 | 0.90 | MAOB (0.65) | NR1H4FFAR4FFAR1MAOBMAOA | |
| SCHEMBL6239053 | 0.81 | FFAR1 (0.75) | FFAR4FFAR1 | |
| SCHEMBL9892644 | 0.79 | PTGS2 (0.52) | FFAR4THRATHRB | |
| SCHEMBL6239017 | 0.79 | FFAR1 (0.51) | FFAR4FFAR1MAOBMAOANR1H2 | |
| SCHEMBL6241283 | 0.79 | FFAR4 (0.78) | FFAR4FFAR1 | |
| SCHEMBL6239647 | 0.79 | PPARD (0.61) | FFAR4FFAR1THRATHRB | |
| SCHEMBL6237904 | 0.78 | FFAR1 (0.57) | FFAR4FFAR1 | |
| SCHEMBL3500758 | 0.77 | MAOB (0.63) | FFAR4FFAR1MAOB | |
| SCHEMBL6237464 | 0.77 | FFAR1 (0.55) | NR1H4FFAR4FFAR1NR1H2NR1H3 | |
| SCHEMBL6240957 | 0.76 | NR1H4 (0.52) | NR1H4FFAR4FFAR1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |