Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033296 | 0.84 | SRD5A2 (0.57) | FFAR1LMNAPOLBGAAPTGS1 | |
| SCHEMBL6239957 | 0.80 | CNR2 (0.51) | IDO1TDO2FFAR1SRD5A2PPARG | |
| SCHEMBL6244413 | 0.79 | CYP1A2 (0.47) | L3MBTL1FFAR1ALDH1A1LMNAHPGD | |
| SCHEMBL25033297 | 0.76 | KLK7 (0.52) | TDP1L3MBTL1ATMFFAR1ALDH1A1 | |
| SCHEMBL27662443 | 0.76 | FFAR1 (0.73) | FFAR1POLBSRD5A2CNR2 | |
| SCHEMBL4565148 | 0.76 | FFAR1 (0.73) | FFAR1POLBSRD5A2CNR2 | |
| SCHEMBL27662594 | 0.76 | FFAR1 (0.73) | FFAR1POLBSRD5A2CNR2 | |
| SCHEMBL6236504 | 0.74 | NAPRT (0.51) | FFAR1SRD5A2ALOX15 | |
| SCHEMBL11490486 | 0.73 | SRD5A2 (0.50) | FFAR1LMNAPOLBGAAPTGS1 | |
| SCHEMBL7798228 | 0.72 | KDM4E (0.55) | TDP1L3MBTL1ATMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |