Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033296 | 0.87 | SRD5A2 (0.57) | F2PRSS1SRD5A2MMP1MMP2 | |
| SCHEMBL8775797 | 0.81 | MMP1 (0.45) | F2PRSS1SRD5A2TBXAS1MMP1 | |
| SCHEMBL6239650 | 0.74 | TDP1 (0.48) | SRD5A2FFAR1ALOX15 | |
| SCHEMBL8775947 | 0.73 | MAPK1 (0.47) | F2PRSS1SMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL25033297 | 0.73 | KLK7 (0.52) | F2PRSS1SRD5A2FFAR1 | |
| SCHEMBL27662594 | 0.73 | FFAR1 (0.73) | SRD5A2FFAR1AKR1B1 | |
| SCHEMBL27662443 | 0.73 | FFAR1 (0.73) | SRD5A2FFAR1AKR1B1 | |
| SCHEMBL11490486 | 0.73 | SRD5A2 (0.50) | SRD5A2FFAR1ALOX15AKR1B1 | |
| SCHEMBL4565148 | 0.73 | FFAR1 (0.73) | SRD5A2FFAR1AKR1B1 | |
| SCHEMBL8775901 | 0.73 | ALDH1A1 (0.47) | SRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |