Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245200 | 0.84 | CNR2 (0.52) | CNR2NR1H4RXRARXRBRXRG | |
| SCHEMBL25033296 | 0.82 | SRD5A2 (0.57) | CNR2PPARGPPARASRD5A2FFAR1 | |
| SCHEMBL6239650 | 0.80 | TDP1 (0.48) | CNR2PPARGPPARASRD5A2IDO1 | |
| SCHEMBL6244413 | 0.77 | CYP1A2 (0.47) | PPARGPPARASRD5A2FFAR1ALOX15 | |
| SCHEMBL6239019 | 0.74 | SLC6A9 (0.47) | SRD5A2FFAR1ALOX15AKR1B1 | |
| SCHEMBL7470957 | 0.73 | IDO1 (0.43) | CNR2PPARGPPARAACP3SRD5A2 | |
| SCHEMBL6236504 | 0.72 | NAPRT (0.51) | SRD5A2FFAR1ALOX15AKR1B1 | |
| SCHEMBL11343236 | 0.71 | IDO1 (0.55) | CNR2ACP3IDO1TDO2 | |
| SCHEMBL4759812 | 0.71 | MAOB (0.65) | NR1H4RXRAPPARAFFAR1 | |
| SCHEMBL4565148 | 0.71 | FFAR1 (0.73) | CNR2SRD5A2FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |