SCHEMBL6239654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6215499	0.92	HTR6 (0.39)	CDK1NTRK1HTR6HTR2CKDM4E
	SCHEMBL6236216	0.92	STK17B (0.42)	CDK1NTRK1HTR6HTR2CKDM4E
	SCHEMBL6210939	0.92	HTR2C (0.42)	CDK1NTRK1HTR6HTR2CKDM4E
	SCHEMBL6212141	0.92	KDM4E (0.43)	CDK1NTRK1HTR6HTR2CKDM4E
	SCHEMBL6212597	0.92	NTRK1 (0.49)	NTRK1CCNT1CDK9PTK2
	SCHEMBL6210924	0.92	JAK2 (0.40)	CDK1HTR6HTR2CKDM4EALDH1A1
	SCHEMBL6211382	0.90	HTR6 (0.52)	HTR6HTR2CKDM4EALDH1A1MAPT
	SCHEMBL6211739	0.89	PTK2 (0.51)	CDK1NTRK1CCNT1CDK9PTK2
	SCHEMBL6829553	0.89	CDK9 (0.40)	CDK1NTRK1HTR6HTR2CKDM4E
	SCHEMBL6212354	0.89	JAK2 (0.38)	CDK1NTRK1HTR6HTR2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.