Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848798 | 0.85 | TSHR (0.41) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL6501572 | 0.80 | TSHR (0.48) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL15063896 | 0.80 | MAPT (0.43) | TSHRALDH1A1CYP3A4GPR35TDP1 | |
| SCHEMBL7744893 | 0.77 | TSHR (0.46) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL21000996 | 0.77 | TSHR (0.47) | TSHRALDH1A1CYP3A4GPR35TDP1 | |
| SCHEMBL13836301 | 0.77 | TDP1 (0.46) | TSHRALDH1A1CYP3A4GPR35TDP1 | |
| SCHEMBL15063757 | 0.76 | TSHR (0.46) | TSHRALDH1A1CYP3A4GPR35TDP1 | |
| SCHEMBL28847435 | 0.73 | TSHR (0.52) | TSHRALDH1A1CYP3A4GPR35TDP1 | |
| SCHEMBL11449422 | 0.73 | MAPT (0.41) | TSHRMAPK1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL29286649 | 0.73 | TSHR (0.42) | TSHRMAPK1ALDH1A1CYP3A4PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116056575-A | Substituted haloalkylsulfonanilide herbicides | FMC公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-0993441-B1 | INHIBITORS OF p38 | VERTEX PHARMA (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6093742-A | TREATMENT OF INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, DESTRUCTIVE BONE DISORDERS, PROLIFERATIVE DISORDERS, INFECTIOUS DISEASES, VIRAL DISEASE, AND NEURODEGENERATIVE DISEASES | VERTEX PHARMACEUTICALS, INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0993441-A1 | INHIBITORS OF p38 | Vertex Pharmaceuticals Incorporated (US) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999000357-A1 | INHIBITORS OF p38 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1999-01-07 | — | — | WO | disclosed |
| US-4960955-A | Process for making 4-chloro-2-methyl-5-nitro-phenol | WELLA AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |