Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531096 | 0.80 | TDP1 (0.48) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6501572 | 0.80 | TSHR (0.48) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6239786 | 0.77 | TSHR (0.46) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL28975371 | 0.76 | ALDH1A1 (0.47) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL5842589 | 0.74 | MAPT (0.46) | ALDH1A1CYP3A4TDP1HIF1AHPGD | |
| SCHEMBL9386232 | 0.73 | TDP1 (0.46) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL9180125 | 0.71 | TSHR (0.62) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL2477068 | 0.71 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL29653309 | 0.71 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL7500593 | 0.70 | CYP3A4 (0.44) | TSHRMAPK1ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| CN-1083836-C | Process for preparation of 3 -(substd. Phenyl) -5 - alkylidene -1, 3 -oxazolidine -2 ,4 -dione derivs. | SAGAMI CHEM RES (JP) | 2002-05-01 | — | — | CN | disclosed |
| EP-0812834-B1 | PROCESS FOR THE PREPARATION OF 3-(SUBSTITUTED PHENYL)-5-ALKYLIDENE-1,3-OXAZOLIDINE-2,4-DIONE DERIVATIVES | SAGAMI CHEM RES (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2001009087-A1 | SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-08 | — | — | WO | disclosed |
| US-6090946-A | Process for the preparation of 3-(substituted phenyl)-5-alkylidene-1,3-oxazolidine-2,4-dione derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-07-18 | — | — | US | disclosed |
| CN-1175946-A | Process for producing 3-substituted phenyl-5-alkylene-1, 3-oxazolidine-2, 4-dione derivative | SAGAMI CHEM RES (JP) | 1998-03-11 | — | — | CN | disclosed |
| EP-0812834-A1 | PROCESS FOR THE PREPARATION OF 3-(SUBSTITUTED PHENYL)-5-ALKYLIDENE-1,3-OXAZOLIDINE-2,4-DIONE DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-4906281-A | Herbicidal 9-arylimino-8-thia-1,6-diazabicyclo [4.3.0]nonane-7-ones (and thiones) | FMC CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | TSHR 4013/4885MAPK1 4375/4885ALDH1A1 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.